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Can you read for what diseases this ad for medecine has been produced?
Also, what are those medecines?
Thanks

Framed calligraphy （Right top),
皇國元祖　Kōkoku ganso - Founder of the Empire
Signed by 河村有平　Kawamura Arihira (Owner of the shop)
Under that, next to the picture on the wall
諸國法得意中　-　Good at the rules of various provinces
Artist's cartouche,
應需　春信筆　On demand painted by Harunobu
Publisher,
博文堂ｘ　Hakubundō x (I cannot read the last character)

Medicines,
天元養氣圓　Tengen yōkien
主治効能　　Main treatment efficiency

小児健脾圓　Shoni kenpien
主治効能　　Main treatment efficiency
For indigestion due to children's week spleen and stomach, lack of appetite, soft stool issues, diarrhea etc.

粒甲丹　Tsubu kōtan
主治効能　　Main treatment efficiency

開達丸　Kaidatsugan
主治効能　　Main treatment efficiency
This is a medicine that eliminates pollution in the body and removes diseases trapped between the membrane plains.

開達散　Kaidatsusan
主治効能は開達丸に同じ　-　Main treatment efficiency is the same as Kaidatsugan

官許　伊勢國小古曽村　河村有平　Officially Licensed　Ise Province, Ogoso Village*、 Kawamura Arihira

取次所　Distributing agency

* Ogoso village; today, Mie Prefecture Yokkaichi City

I intend to return to the items I didn't answer this time due lack of time.

With regards,
I.Nagy

Continuation,
天元養氣圓　Tengen yōkien
主治効能　　Main treatment efficiency
Hepatic encephalopathy, colic pain of liver, gallstones, sunstroke, pain in lower abdomen, lumps in abdomen (cancer), asthma, diarrhea

粒甲丹　Tsubu kōtan
主治効能　　Main treatment efficiency
Exactly same as those listed under "Tengen yokien"
above

Taking a closer look at the other medicines,
"Shoni kempien" and "Kaidatsugan"
- except of the accompanying descriptions, the same disease names are listed.
In other words, practically all four medicines were good for the same diseases.

Most probably, this shop was a medicine manufacturer and distributor.

With regards,
I.Nagy

Again, a lot of thanks!!

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